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Patients with elevated baseline inflammatory markers (CRP, IL-6) or copper metabolism disorders may face higher risk of adverse reactions

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doi:10.1016/0016-5085(90)90290-H.[Crossref], [PubMed], [Web of Science ] , [Google Scholar]) discovered that DSS induced lesions in a manner similar to human ulcerative colitis after 610 days of ingestion of 310% DSS in drinking water in mice